澳洲新生牛血清采自出生20天內(nèi)的新生牛，是指新生牛血液凝固后，去除血漿中纖維蛋白原及某些凝血因子后分離出的淡黃色有乳光液體。
新生牛血清是細(xì)胞培養(yǎng)中用量較大的天然培養(yǎng)基，含有豐富的細(xì)胞生長(zhǎng)必須的營(yíng)養(yǎng)成分，具有極為重要的功能，一般添加比例為：5-20%。血清中含有各種氨基酸、維生素、無機(jī)物、脂類物質(zhì)等這些維持細(xì)胞生長(zhǎng)必須的營(yíng)養(yǎng)物質(zhì)，也含有胰島素、氫化可的松、地塞米松、bFGF、EGF、PDGF、轉(zhuǎn)鐵蛋白等可促進(jìn)細(xì)胞生長(zhǎng)的激素、生長(zhǎng)因子及結(jié)合蛋白。此外，血清還有解毒、緩沖、抑制蛋白酶活性等作用保護(hù)細(xì)胞不受傷害。
依科賽新生牛血清均采自非疫區(qū)的健康牛，經(jīng)無菌采集、批量混合、3級(jí)100 nm過濾器過濾分裝而成，不含支原體和BVDV、PI3、BPV等牛源病毒。
Zhong B et al. The Ubiquitin Ligase RNF5Regulates Antiviral Responses by Mediating Degradation of the Adaptor ProteinMITA. Volume 30, ISSUE 3, P397-407, March 20, 2009. Read more（PubMed: 19285439）
Li Q et al. CRISPR–Cas9-mediatedbase-editing screening in mice identifies DND1 amino acids that are criticalfor primordial germ cell development. Nature cell biology,2018. Read more（PubMed: 30718859）
Luo YL etal. Macrophage-Specific in Vivo Gene Editing Using Cationic Lipid-AssistedPolymeric Nanoparticles. ACS Nano 2018, 12, 994?1005.Read more（PubMed：29314827）
Du JZ et al. Smart Superstructureswith Ultrahigh pHSensitivity for Targeting Acidic Tumor. ACS Nano 2016, 10,6753?6761.Read more（PubMed：27244096）
Chen X et al. Long noncoding RNA LBCS inhibits self-renewal andchemoresistance of bladder cancer stem cells through epigenetic silencing ofSOX2. Clinical Cancer Research ,2018. Read more（PubMed：30397178）
Li HJ et al. Stimuli-responsiveclustered nanoparticles for improved tumor penetration and therapeuticefficacy. PNAS,2018. Read more（PubMed：27035960)
Li Y et al. ISG56 is anegative-feedback regulator of virus-triggered signaling and cellular antiviral response. PNAS, 2009,106(19): 7945-7950.Read more（PubMed：19416887)
Wang JL et al. The effect ofsurface poly(ethylene glycol) length on in vivo drug delivery behaviors ofpolymeric nanoparticles. Biomaterials 182（2018）104-113.Read more（PubMed：30114562)
